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BRCA+

BRCA+

With Test4Cancer® BRCA+ you can test whether you have a highly increased risk of breast, ovarian, or prostate cancers. Clinically relevant genes associated with a moderately increased risk of breast and ovarian cancers are not included in GeneMate® BRCA+.

For a complete assessment of your breast and ovarian cancer risk, please see Test4Cancer® Breast & Ovarian.

Who is this test suitable for?

Not all cancers need to present in the family in order to suspect hereditary cancer. Early onset of cancer or several instances of the same or genetically related cancer types in a family increase the likelihood that it is hereditary. Women with ovarian cancer or triple negative breast cancer are recommended genetic testing despite a lack of family history.

Women with a family history of breast, ovarian, prostate, and/or pancreatic cancer.

Women who have been diagnosed with ovarian cancer or triple negative breast cancer.

Women who have been diagnosed with breast cancer with a family history of breast, ovarian, prostate, and/or pancreatic cancer.

Men with a family history of breast, ovarian, prostate, and/or pancreatic cancer.

Men who have been diagnosed with prostate or breast cancer.

What does a positive test mean for my risk?

How much your risk is increased and for which cancer(s) depends on which gene is varied, as well as your family history including age at diagnosis.

Women who’s Test4Cancer® BRCA+ test is positive have a highly increased risk of breast cancer and a moderately to highly increased risk of ovarian cancer.

Men who’s Test4Cancer® BRCA+ test is positive have a highly increased risk of developing prostate cancer (BRCA2) and a somewhat increased risk of breast cancer.

How can I manage my risk?

Women

Healthy women with an increased risk of breast cancer will be offered mammography screening and MRI of the breasts, or surgical removal of the breasts with the intent of preventing breast cancer.

Healthy women with an increased risk of gynecological cancers may consider surgical removal of ovaries and fallopian tubes and/or uterus with the intent of preventing cancer in these organs.

Men

Healthy men with an increased risk of prostate cancer (only BRCA2 variants) will be offered prostate screening in the form of PSA testing and palpation.

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