With Test4 Breast & Ovarian you can test your hereditary risk for breast cancer and ovarian cancer. The genes included in the test are those that have been shown to be linked to hereditary breast cancer and/or hereditary ovarian cancer and where there are clinical measures in the form of preventive measures or control programs.
Test4Cancer® Breast & Ovarian also analyzes genes associated with a moderately increased risk. Some of the genes involved are linked to rare hereditary cancer syndromes, where breast cancer can be one of the symptoms.
Women who have a family history of breast, ovarian, prostate and/or pancreatic cancer.
Women diagnosed with triple-negative breast or ovarian cancer.
Women who have been diagnosed with breast cancer and have a family history of breast, ovarian, prostate and/or pancreatic cancer.
Women who have a family history of breast cancer and any of the cancers below and women diagnosed with breast cancer in combination with any of the cancers below:
How much your risk is increased and for which form(s) of cancer depends on which gene the variant is in, the number of close relatives with cancer and their age at onset.
Women with a positive Test4Cancer® Breast & Ovarian test may have a moderately to greatly increased lifetime risk of breast and/or ovarian cancer.
In some cases, the risk of other forms of cancer may also be increased. These include stomach cancer, thyroid cancer, uterine cancer, colon and rectal cancer, sarcoma, brain tumors, and adrenal cancer.
For healthy carriers, the measures aim to reduce the risk of developing cancer or to detect cancer early to give a better prognosis. Extent, age at onset and frequency vary depending on family history and which gene is varied.
Measures for healthy women at increased risk of breast cancer include increased mammography checks and possibly MRI of the breasts, or alternatively, surgical removal of the breasts for preventive purposes. Measures for healthy women at increased risk of ovarian cancer include surgical removal of the fallopian tubes and ovaries for prevention. Screening programs for thyroid cancer, colon and rectal cancer, kidney cancer, stomach cancer, small bowel cancer, pancreatic cancer and uterine cancer may also be relevant.
